After considerable accomplishments, he spies the legendary James Bond (Daniel Craig) is attached. The first task in the new location is to track terrorist Mollaka in Madagascar (Sébastien Foucan).

Things have not been planned in advance and is not complete as desired, so he decided to operate independently with MI6 and himself investigated from the clues to this terrorist group payment.

While on duty, James Bond encounters Dimitrios and Solange (Caterina Murino), his wife. He discovered that are associated with Le Chiffre Dimitrios (Mads Mikkensel), a hooded black French society specialized profits gained from the casino to the next hand to terrorists.

According to investigators from Intelligence Agency MI6, Le Chiffre has been a huge amount of losses, to seek to return the money, he planned the Royal Casino silver Khan in Montenegro. Duties of Agent 007 is to mask a thirst for money to gamblers with Le Chiffre tournament. If he wins, the whole organization of Le Chiffre will disappear.